TY - JOUR AU - Ana Arana-Guajardo AU - Carlos Cámara-Lemarroy AU - Erick Rendón- Ramírez AU - Joel Jáquez-Quintana AU - Juan Góngora -Rivera AU - Dionicio Galarza-Delgado PY - 2012/01/10 Y2 - 2024/03/28 TI - Wernicke Encephalopathy Presenting in a Patient with Severe Acute Pancreatitis JF - JOP. Journal of the Pancreas JA - JOP VL - 13 IS - 1 SE - CASE REPORTS DO - 10.6092/1590-8577/469 UR - http://www.serena.unina.it/index.php/jop/article/view/urn%3Anbn%3Ait%3Aunina-3388 AB - Context Acute pancreatitis can lead to prolonged fasting and malnutrition. Many metabolic changes, including thiamine deficiency, may lead to the well know pancreatic encephalopathy. In this condition however the thiamine deficiency is rarely suspected. Case report We report the case of a 17-year-old woman with severe acute pancreatitis who developed mental status changes and ophthalmoplegia. A magnetic resonance image showed hyperintensive signals in periventricular areas, medial thalamus, and mammillary bodies, findings consistent with the diagnosis of Wernicke encephalopathy. Thiamine treatment reversed neurological complications. Conclusion Wernicke encephalopathy secondary to thiamine deficiency should be considered as a possible cause of acute mental status changes in patients with acute pancreatitis and malnutrition. Prophylactic doses of thiamine could be considered in susceptible patients. ER -