TY - JOUR AU - Andrew Beamish AU - S Roberts AU - James Ansell AU - Bilal Al-Sarireh PY - 2012/01/10 Y2 - 2024/03/29 TI - Endoluminal Ultrasound of Neoduodenum Following Pancreas-Preserving Total Duodenectomy for Familial Adenomatous Polyposis JF - JOP. Journal of the Pancreas JA - JOP VL - 13 IS - 1 SE - CASE REPORTS DO - 10.6092/1590-8577/471 UR - http://www.serena.unina.it/index.php/jop/article/view/urn%3Anbn%3Ait%3Aunina-3390 AB - Context Familial adenomatous polyposis affects around 2-10 per 100,000 population. Untreated, it inevitably leads to colon cancer. Prophylactic panproctocolectomy has led to improved survival. The resulting extension to follow-up has revealed that 70-100% of patients with familial adenomatous polyposis go on to develop duodenal polyposis and the lifetime risk of duodenal carcinoma in this group is up to 10%. Treatment for those not locally resectable requires pancreaticoduodenectomy. In recent years, pancreas-preserving total duodenectomy has emerged as a safe alternative to pancreaticoduodenectomy. Endoscopy has previously been safely performed in patients following pancreas-preserving total duodenectomy. Case report We report successful endoscopic ultrasound (EUS) assessment and trans-neoduodenal EUS-guided fine needle aspiration biopsy (EUS-FNA) of the pancreas and adjacent tissue in a 45-year-old man with familial adenomatous polyposis who has previously undergone pancreas-preserving total duodenectomy. EUS confirmed the mass was most likely to represent a metastasis in a local lymph node. EUS-FNA confirmed invasive malignancy. A Kausch-Whipple pancreaticoduodenectomy was performed successfully and post-operative recovery has been excellent. Conclusion The authors consider this to be the first report of successful EUS and EUS-FNA performed through the neoduodenum fashioned during pancreas-preserving total duodenectomy. ER -