Pancreas Cancer-Associated Polymyositis of the Legs Regressing After Cephalic Duodenopancreatectomy: Case Report and Review of the Literature

  • Koceila Lamine Amroun Service of General, Digestive and Endocrine Surgery, "Robert-Debré" Hospital. Reims, France
  • Louis de Mestier Service of Hepatogastroenterology and Digestive Oncology, "Robert-Debré" Hospital. Reims, France
  • Sophie Deguelte-Lardiere Service of General, Digestive and Endocrine Surgery, "Robert-Debré" Hospital. Reims, France
  • Marie-Danièle Diebold Service of Anatomy and Pathological Cytology, "Robert-Debré" Hospital. Reims, France
  • Olivier Bouché Service of Hepatogastroenterology and Digestive Oncology, "Robert-Debré" Hospital. Reims, France
  • Reza Kianmanesh Service of General, Digestive and Endocrine Surgery, "Robert-Debré" Hospital. Reims, France
Keywords: General Surgery, Pancreatic Neoplasms, Pancreaticoduodenectomy, Paraneoplastic Syndromes, Polymyositis

Abstract

Context Inflammatory myopathy, such as polymyositis, has been widely reported as paraneoplastic syndrome associated with various malignancies. However, its association with pancreas adenocarcinoma is very uncommon. Case report A case of a patient with paraneoplastic polymyositis of both legs associated with pancreatic adenocarcinoma is reported here. The diagnosis of polymyositis was highlighted by MRI and confirmed by histopathological examination. The surgical resection of the primary tumor led to the complete resolution of polymyositis with no further recurrence despite later metastases. Conclusion The association between pancreatic cancer and paraneoplastic polymyositis is very uncommon and has to be recognized by clinicians.

Image: MRI (T1) axial section of thigh with gadolinium injection.

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MRI (T1) axial section of thigh with gadolinium injection
Published
2012-11-10
How to Cite
AmrounK., de MestierL., Deguelte-LardiereS., DieboldM.-D., BouchéO., & KianmaneshR. (2012). Pancreas Cancer-Associated Polymyositis of the Legs Regressing After Cephalic Duodenopancreatectomy: Case Report and Review of the Literature. JOP. Journal of the Pancreas, 13(6), 674-676. https://doi.org/10.6092/1590-8577/1183