New Developments in the Management of Borderline Resectable Pancreatic Cancer

  • Jaya Sharma Division of Hematology Oncology, Department of Medicine, Tufts Medical Center. Boston, MA, USA
  • John Ng Department of Radiation Oncology, Weill Cornell Medical Center. New York, NY, USA
  • Martin D Goodman Department of Surgery, Tufts Medical Center. Boston, MA, USA
  • Muhammad Wasif Saif Division of Hematology Oncology, Department of Medicine, Tufts Medical Center. Boston, MA, USA
Keywords: Neoadjuvant Therapy, Pancreatic Neoplasms, Radiosurgery

Abstract

The optimal management of borderline resectable pancreatic cancer remains unclear. Neoadjuvant chemoradiation remains the most common approach in the United States, while neoadjuvant chemotherapy alone is also widely utilized and has demonstrated efficacy but there has been no clear consensus about a regimen that would be most beneficial in this setting. We will discuss three abstracts that were presented in the 2013 ASCO Gastrointestinal Cancers Symposium in which various regimens were evaluated in the neoadjuvant setting.

Image: New sign at the entrance of Tufts Medical Center on the day of its renaming (March 4, 2008). (Wikimedia Commons)

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Author Biographies

Jaya Sharma, Division of Hematology Oncology, Department of Medicine, Tufts Medical Center. Boston, MA, USA

Division of Hematology Onocology, Department of Medicine

 

John Ng, Department of Radiation Oncology, Weill Cornell Medical Center. New York, NY, USA
Department of Radiation Oncology
Muhammad Wasif Saif, Division of Hematology Oncology, Department of Medicine, Tufts Medical Center. Boston, MA, USA

Director, Gastrointestinal Oncology Program

Leader, Experimental Therapeutics Program

Division of Hematology Oncology

References

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Jonathan Ben Ashman, Adyr A Moss, Matthew D. Callister, Kunam S Reddy, David C Mulligan, Leonard L. Gunderson, Mitesh J. Borad. Neoadjuvant chemoradiation and intraoperative electron irradiation for locally unresectable/borderline resectable pancreas adenocarcinoma. J Clin Oncol. 2012;30, Suppl 4, Abstract 327.

Jose Mario Pimiento, Tai Hutchinson, Jill M. Weber, Manish R. Patel, Pamela Joy Hodul, Michael D. Chuong, et al. Multimodality therapy for borderline resectable pancreatic cancer: A single-institution experience. J Clin Oncol 2012. 2012;30, Suppl 4, Abstract 280.

Pavlos Papavasiliou, Jonathan R Piposar, Rodrigo Arrangoiz, Kathryn T Chen, Fang Zhu, Yun Shin Chun et al.. Margin status and neoadjuvant chemoradiation in patients with borderline resectable pancreatic cancer. J Clin Oncol. 2012;30, Suppl 4, Abstract 304.

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Tufts Medical Center. Boston, MA, USA
Published
2013-03-10
How to Cite
SharmaJ., NgJ., GoodmanM., & SaifM. (2013). New Developments in the Management of Borderline Resectable Pancreatic Cancer. JOP. Journal of the Pancreas, 14(2), 123-125. https://doi.org/10.6092/1590-8577/1473
Section
Highlights from the “2013 ASCO Gastrointestinal Cancers Symposium”. San Francisco, CA, USA. January 24-26, 2013