Collision Tumors: Pancreatic Adenocarcinoma and Mantle Cell Lymphoma

  • Constantin A Dasanu Department of Hematology-Oncology, St. Francis Hospital and Medical Center. Hartford, CT, USA
  • Alexei Shimanovsky Department of Internal Medicine, University of Connecticut Medical Center. Farmington, CT, USA
  • Edyta K Rotundo Department of Anatomic and Clinical Pathology, St. Francis Hospital and Medical Center. Hartford, CT, USA
  • Anthony F Posteraro Department of Radiology, St. Francis Hospital and Medical Center. Hartford, CT, USA
  • Dennis L Cooper Department of Hematology, Yale University School of Medicine. New Haven, CT, USA
  • Jonessa A Atienza Department of Internal Medicine, University of Connecticut Medical Center. Farmington, CT, USA
Keywords: collision tumors, pancreatic adenocarcinoma, mantle cell lymphoma, cyclin D1


Context Collision tumors are very rare entities composed of two or more distinct tumor components, each separated by normal tissue. Perhaps due to technical advances in the last decade, the incidence of collision tumors has been on the rise. To the best of our knowledge, collision tumors featuring mantle cell lymphoma and pancreatic adenocarcinoma have not been previously described in the scientific literature. Case report For the first time, we describe herein the clinical course of a collision tumor between pancreatic adenocarcinoma and mantle cell lymphoma. Discussion We hypothesize several aspects in the pathogenesis of a such event and review the existing literature on collision tumors.

Image: PET/CT scan showing extensive FDG-avid tumor featuring.


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Author Biography

Constantin A Dasanu, Department of Hematology-Oncology, St. Francis Hospital and Medical Center. Hartford, CT, USA
Department of Hematology-Oncology, Saint Francis Hospital and Medical Center, Hartford, CT, USA


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PET/CT scan showing extensive FDG-avid tumor featuring
How to Cite
DasanuC., ShimanovskyA., RotundoE., PosteraroA., CooperD., & AtienzaJ. (2013). Collision Tumors: Pancreatic Adenocarcinoma and Mantle Cell Lymphoma. JOP. Journal of the Pancreas, 14(4), 458-462.