Case Report of Pancreatic Dermoid Cyst: Can Fine Needle Aspiration Make the Diagnosis?

  • Daniel A Lyons Division of Surgical Oncology, Department of Surgery, University of Missouri-Columbia. Columbia, MO, USA
  • Emily A Coberly Department of Pathology, University of Missouri-Columbia. Columbia, MO, USA
  • Ghassan M Hammoud Division of Gastroenterology, Department of Medicine, University of Missouri-Columbia. Columbia, MO, USA
  • Michael B Nicholl Ellis Fischel Cancer Center. Columbia, MO, USA
Keywords: Biopsy, Fine-Needle, Cyst Fluid, Endosonography, Pancreatic Cyst

Abstract

Context Pancreatic dermoid cysts are rare, benign, germ cell tumors and part of the differential diagnosis for cystic neoplasms of the pancreas. Case report A 35-year-old man presented with an incidentally discovered, 2 cm cystic pancreatic neoplasm of the pancreatic tail identified on CT scan. Endoscopic ultrasound (EUS) revealed a complex, honeycomb lesion. Fine needle aspiration (FNA) yielded a sample of whitish, necrotic material containing histiocytes, benign epithelial cells, and lymphocytes. After distal pancreatectomy and splenectomy was performed, histology revealed a cyst lined by stratified squamous epithelium with benign sebaceous units consistent with a pancreatic dermoid cysts. Discussion Although axial imaging reliably detects cystic neoplasms of the pancreas, diagnostic criteria for rare lesions are lacking; therefore alternative modalities such as EUS/FNA can be utilized. This case report highlights the EUS and FNA findings associated with pancreatic dermoid cysts.

Image: Stratified squamous epithelium, sebaceous units, and surrounding lymphocyte infiltration.

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Author Biographies

Daniel A Lyons, Division of Surgical Oncology, Department of Surgery, University of Missouri-Columbia. Columbia, MO, USA
Department of Surgery
Emily A Coberly, Department of Pathology, University of Missouri-Columbia. Columbia, MO, USA
Department of Pathology
Ghassan M Hammoud, Division of Gastroenterology, Department of Medicine, University of Missouri-Columbia. Columbia, MO, USA
Division of Gastroenterology
Michael B Nicholl, Ellis Fischel Cancer Center. Columbia, MO, USA
Department of Surgery,Division of Surgical Oncology,Assistant Professor of Clinical Surgery

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Stratified squamous epithelium, sebaceous units, and surrounding lymphocyte infiltration
Published
2013-11-10
How to Cite
LyonsD., CoberlyE., HammoudG., & NichollM. (2013). Case Report of Pancreatic Dermoid Cyst: Can Fine Needle Aspiration Make the Diagnosis?. JOP. Journal of the Pancreas, 14(6), 653-656. https://doi.org/10.6092/1590-8577/1787