A Case of Recurrent Acute Pancreatitis Due to Intra-Articular Corticosteroid Injection
Context Corticosteroid is a well-established cause of drug-induced pancreatitis. However, acute pancreatitis from intra-articular injection of corticosteroid has never been described. Case report A 69-year-old male presented with acute abdominal pain and was diagnosed with acute pancreatitis. The patient had one episode of acute pancreatitis two year earlier. Both episodes occurred after intra-articular cortisone injection. Investigations for other causes of pancreatitis were negative. Conclusion We report the first case of acute pancreatitis from intra-articular corticosteroid injection. Physicians should be aware of this adverse reaction of corticosteroid that can even occur with local administration.
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Trivedi CD, Pitchumoni CS. Drug-induced pancreatitis: an update. J Clin Gastroenterol 2005; 8:709-11. [PMID: 16082282]
Karch FE, Lasagna L. Adverse drug reactions. A critical review. JAMA 1975; 234:1236-41. [PMID: 1242749]
Nitsche C, Maertin S, Scheiber J, Ritter CA, Lerch MM, Mayerle J. Drug-induced pancreatitis. Curr Gastroenterol Rep 2012;14:131-8 [PMID: 22314811]
Yoshizawa Y, Ogasa S, Izaki S, Kitamura K. Corticosteroid-induced pancreatitis in patients with autoimmune bullous disease: Case report and prospective study. Dermatology 1999; 198:304-6. [PMID: 10393460]
Lansang MC, Farmer T, Kennedy L. Diagnosing the unrecognized systemic absorption of inta-articular and epidural steroid injections. Endocr Pract 2009; 15:225-8. [PMID: 19364690]
O’sullivan MM, Rumfeld WR, Jones MK, Williams BD. Cushing’s syndrome with suppression of the hypothalamic-pituitary-adrenal axis after intra-articular steroid injections. Ann Rheum Dis 1985; 44:561-3. [PMID: 4026419]
Copyright (c) 2014 Patompong Ungprasert, Nitipong Permpalung, Sarawut Summachiwakij, Wuttiporn Manatsathit
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