A Case of Recurrent Acute Pancreatitis Due to Intra-Articular Corticosteroid Injection
Abstract
Context Corticosteroid is a well-established cause of drug-induced pancreatitis. However, acute pancreatitis from intra-articular injection of corticosteroid has never been described. Case report A 69-year-old male presented with acute abdominal pain and was diagnosed with acute pancreatitis. The patient had one episode of acute pancreatitis two year earlier. Both episodes occurred after intra-articular cortisone injection. Investigations for other causes of pancreatitis were negative. Conclusion We report the first case of acute pancreatitis from intra-articular corticosteroid injection. Physicians should be aware of this adverse reaction of corticosteroid that can even occur with local administration.
Image: Bassett Medical Center. Cooperstown, NY, USA (logo)
Downloads
References
Trivedi CD, Pitchumoni CS. Drug-induced pancreatitis: an update. J Clin Gastroenterol 2005; 8:709-11. [PMID: 16082282]
Karch FE, Lasagna L. Adverse drug reactions. A critical review. JAMA 1975; 234:1236-41. [PMID: 1242749]
Nitsche C, Maertin S, Scheiber J, Ritter CA, Lerch MM, Mayerle J. Drug-induced pancreatitis. Curr Gastroenterol Rep 2012;14:131-8 [PMID: 22314811]
Yoshizawa Y, Ogasa S, Izaki S, Kitamura K. Corticosteroid-induced pancreatitis in patients with autoimmune bullous disease: Case report and prospective study. Dermatology 1999; 198:304-6. [PMID: 10393460]
Lansang MC, Farmer T, Kennedy L. Diagnosing the unrecognized systemic absorption of inta-articular and epidural steroid injections. Endocr Pract 2009; 15:225-8. [PMID: 19364690]
O’sullivan MM, Rumfeld WR, Jones MK, Williams BD. Cushing’s syndrome with suppression of the hypothalamic-pituitary-adrenal axis after intra-articular steroid injections. Ann Rheum Dis 1985; 44:561-3. [PMID: 4026419]

Copyright (c) 2014 Patompong Ungprasert, Nitipong Permpalung, Sarawut Summachiwakij, Wuttiporn Manatsathit

This work is licensed under a Creative Commons Attribution 4.0 International License.
As a member of Publisher International Linking Association, PILA, iMedPub Group’s JOP follows the Creative Commons Attribution License and Scholars Open Access publishing policies. Journal of the Pancreas is the Council Contributor Member of Council of Science Editors (CSE) and following the CSE slogan Education, Ethics, and Evidence for Editors.