The Role of Nonsteroidal Anti-inflammatory Drugs in the Prevention of Post Endoscopic Retrograde Cholangiopancreatography Pancreatitis

  • Imran Sheikh Division of Gastroenterology, University of Tennessee Health Science Center, Memphis, TN, USA
  • Eric Fontenot Department of Medicine, University of Tennessee Health Science Center, Memphis, TN, USA
  • Nisheet Waghray Division of Gastroenterology, Metro Health Medical Center, Case Western Reserve University, Cleveland, OH, USA
  • Mohammad K Ismail Division of Gastroenterology, University of Tennessee Health Science Center, Memphis, TN, USA
  • Claudio Tombazzi Division of Gastroenterology, University of Tennessee Health Science Center, Memphis, TN, USA
  • J Lacey Smith Division of Gastroenterology, University of Tennessee Health Science Center, Memphis, TN, USA
Keywords: Anti-Inflammatory Agents, Cholangiopancreatography, Endoscopic Retrograde /adverse effects, Pancreatitis /prevention and control

Abstract

Post-ERCP pancreatitis (PEP) is the most common major complication associated with ERCP. Beginning with an overview of the risk factors for the development of PEP, this review introduces the mechanism of injury in PEP and the role of pharmacological prevention. NSAIDs are increasingly found to offer prevention against the development of PEP, and their mechanism and supportive data are summarized, especially in relationship to the practice of prophylactic pancreatic duct stenting.

Image: University of Tennessee Health Science Center. Memphis, TN, USA.

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University of Tennessee Health Science Center. Memphis, TN, USA.
Published
2014-05-27
How to Cite
SheikhI., FontenotE., WaghrayN., IsmailM., TombazziC., & SmithJ. (2014). The Role of Nonsteroidal Anti-inflammatory Drugs in the Prevention of Post Endoscopic Retrograde Cholangiopancreatography Pancreatitis. JOP. Journal of the Pancreas, 15(3), 219-224. https://doi.org/10.6092/1590-8577/2258