Intraductal Papillary Mucinous Neoplasms of the Pancreas (IPMNs): New Insights on Clinical Outcomes and Malignant Progression

  • Jack Khouri Department of Medicine, Division of Hematology and Oncology, Tufts Medical Center. Boston, MA, USA
  • Muhammad Wasif Saif Department of Medicine, Division of Hematology and Oncology, Tufts Medical Center. Boston, MA, USA
Keywords: Carcinoma, Pancreatic Ductal, Disease Management, Neoplasms, Cystic, Mucinous, and Serous

Abstract

Intraductal papillary mucinous neoplasms (IPMNs) are cystic tumors of the pancreas that can progress into invasive carcinomas. Main duct IPMN is usually treated with surgery while branch duct IPMN is surgically resected if it is high risk based on certain features of the tumor (mostly radiographic) that do have some limitations. Predicting the risk of malignant progression has been lately the main focus of research especially that comprehending the molecular pathogenesis of the disease has emerged as a valuable means to better understand the disease and thus guide disease management. We will present two abstracts from the ASCO Annual Meeting. The first compares the clinical outcomes of pancreatic ductal carcinoma and IPMN associated cancer, and the second looks at the pathogenesis of the disease at the cellular and molecular levels to predict high risk disease.

Image: Stained glass windows by Tommaso Juglaris at Goddard  Chapel at Tufts University. Medford, MA, USA

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References

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Stained glass windows by Tommaso Juglaris at Goddard  Chapel at Tufts University. Medford, MA, USA
Published
2014-07-28
How to Cite
KhouriJ., & SaifM. (2014). Intraductal Papillary Mucinous Neoplasms of the Pancreas (IPMNs): New Insights on Clinical Outcomes and Malignant Progression. JOP. Journal of the Pancreas, 15(4), 310-312. https://doi.org/10.6092/1590-8577/2676
Section
Highlights from the “50th ASCO Annual Meeting 2014”. Chicago, IL, USA. May 30 - June 3, 2014