Pharmacogenetics and Other Molecular Targets in the Management of Pancreatic Adenocarcinoma

  • Eirini Merika West London Renal and Transplant Centre, Hammersmith Hospital, Imperial College London. London, United Kingdom
  • Konstantinos N Syrigos Oncology Unit, Third Department of Medicine, Athens Medical School. Athens, Greece
  • Muhammad Wasif Saif Section of Medical Oncology, Yale University School of Medicine. New Haven, CT, USA
Keywords: BRAF protein, human, epidermal growth factor receptor-neu receptor, KRAS protein, Pancreatic Neoplasms, Pharmacogenetics, Polymorphism, Single Nucleotide


Among various abstracts presented at the Annual Meeting of the American Society of Clinical Oncology (ASCO) held in Chicago, June 2010, four interesting abstracts focusing on pancreatic cancer merit further discussion in this post-ASCO commentary as they potentially provide insight to clinicians and hope to patients. These abstracts point to the future of pancreatic cancer management through identification of molecular targets and prognostic factors to overcome the limits of efficacious chemotherapy delivery.

Image: XPD protein (with permission of Department of Energy, Lawrence Berkeley National Laboratory, CA, USA).


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How to Cite
MerikaE., SyrigosK., & SaifM. (2010). Pharmacogenetics and Other Molecular Targets in the Management of Pancreatic Adenocarcinoma. JOP. Journal of the Pancreas, 11(4), 328-330.
Highlights from the “2010 ASCO Annual Meeting”. Chicago, IL, USA. June 4-8, 2010