Severe Hypophosphatemia in a Patient with Acute Pancreatitis

Evagelos Rizos; George Alexandrides; Moses S Elisaf

doi:10.6092/1590-8577/377

Evagelos Rizos Department of Internal Medicine, Medical School, University of Ioannina. Ioannina, Greece
George Alexandrides Department of Internal Medicine, Medical School, University of Ioannina. Ioannina, Greece
Moses S Elisaf Department of Internal Medicine, Medical School, University of Ioannina. Ioannina, Greece

DOI: https://doi.org/10.6092/1590-8577/377

Keywords: Hypophosphatemia, Pancreatitis, Phosphorus Metabolism Disorders, Water-Electrolyte Imbalance

Abstract

Context We describe a patient with alcohol-induced pancreatitis who developed severe life-threatening hypophosphatemia of multifactorial origin during hospitalization. Case Report Decreased phosphate levels along with urine phosphate wasting were already noticed on the patient's admission due to underlying chronic alcoholism. However, a further deterioration of hypophosphatemia appeared on the second day of hospitalization presumably resulting from an increased transfer of phosphate from extracellular to intracellular fluid. Conclusions Phosphate deficiency is often overlooked in patients with acute pancreatitis. Our case emphasizes that serum phosphate levels should be checked along with serum calcium levels in patients with acute pancreatitis, especially in alcoholic patients.

Image: Theodore Papagianni sculpture at the University of Ioannina, Greece.

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