Microvascular Complications in Cystic Fibrosis-Related Diabetes Mellitus: a Case Report.

  • Andrew IR Scott Adult Cystic Fibrosis Unit, University of Queensland. Brisbane, Australia
  • Belinda E Clarke Department of Anatomical Pathology, The Prince Charles Hospital. Brisbane, Australia
  • Helen Healy Department of Renal Medicine, Royal Brisbane Hospital. Brisbane, Australia
  • Michael D'Emden Department of Endocrinology, Royal Brisbane Hospital. Brisbane, Australia
  • Scott C Bell Adult Cystic Fibrosis Unit, University of Queensland. Brisbane, Australia
Keywords: Amitriptyline, Ceftazidime, Cystic Fibrosis (therapy), Diabetes Mellitus (therapy), Diabetic Angiopathies, Diabetic Nephropathies, Diabetic Retinopathy, Diclofenac, HLA-DR Antigens, Lisinopril

Abstract

Context The prevalence of cystic fibrosis-related diabetes mellitus is increasing and is associated with increased survival from cystic fibrosis. Case Report This study describes a case of the premature onset of disabling and widespread microvascular complications resulting from cystic fibrosis-related diabetes mellitus. Previously asymptomatic retinopathy was diagnosed on recognition of diabetic nephropathy. Conclusions The treatment of pulmonary exacerbations has become more complex due to the nephrotoxic potential of intravenous aminoglycoside drugs which are frequently used to control chronic Pseudomonas infection in cystic fibrosis.

Image: Renal biopsy: glomeruli with a global increase in the mesangial matrix.

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References

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Renal biopsy: glomeruli with a global increase in the mesangial matrix
Published
2016-06-13
How to Cite
ScottA., ClarkeB., HealyH., D’EmdenM., & BellS. (2016). Microvascular Complications in Cystic Fibrosis-Related Diabetes Mellitus: a Case Report. JOP. Journal of the Pancreas, 1(4), 208-210. https://doi.org/10.6092/1590-8577/378