Micronutrient Therapy for Chronic Pancreatitis: Rationale and Impact

  • Joan M Braganza Honorary Consultant Gastroenterologist, Royal Infirmary. Manchester, United Kingdom
  • Thomas L Dormandy Emeritus Professor of Chemical Pathology, London University. London, United Kingdom
Keywords: Antioxidants, Ascorbic Acid, Cystic Fibrosis, Cytochrome P-450 Enzyme System, Mast Cells, Methionine

Abstract

Micronutrient therapy, designed to buttress tissue methyl and thiol groups, curbs attacks and controls background pain in patients with chronic pancreatitis, irrespective of aetiology. This outcome and the premises upon which it is based facilitate an understanding of links with mutations in genes for hereditary pancreatitis and cystic fibrosis, demography, and predisposition to pancreatic cancer. Above all, there is an opportunity for prophylaxis in individuals at high risk of developing the disease.

Image: A template for the pathogenesis of chronic pancreatitis.

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A template for the pathogenesis of chronic pancreatitis
Published
2010-03-05
How to Cite
BraganzaJ., & DormandyT. (2010). Micronutrient Therapy for Chronic Pancreatitis: Rationale and Impact. JOP. Journal of the Pancreas, 11(2), 99-112. https://doi.org/10.6092/1590-8577/3841