Intraductal Oncocytic Papillary Neoplasm of the Pancreas: A Radio-Pathological Case Study

  • Michael A Fischer Institute of Diagnostic Radiology, University Hospital Zurich. Zurich, Switzerland
  • Olivio Donati Institute of Diagnostic Radiology, University Hospital Zurich. Zurich, Switzerland
  • Stefan Heinrich Clinic of Visceral and Transplant Surgery, University Hospital Zurich. Zurich, Switzerland
  • Achim Weber Institute of Surgical Pathology, University Hospital Zurich. Zurich, Switzerland
  • Thomas F Hany Clinic of Nuclear Medicine, University Hospital Zurich. Zurich, Switzerland
  • Davide Soldini
  • Hatem Alkadhi Institute of Diagnostic Radiology, University Hospital Zurich. Zurich, Switzerland
  • Borut Marincek Institute of Diagnostic Radiology, University Hospital Zurich. Zurich, Switzerland
  • Hans Scheffel Institute of Diagnostic Radiology, University Hospital Zurich. Zurich, Switzerland
Keywords: Carcinoma, Pancreatic Ductal, Diffusion Magnetic Resonance Imaging, Fluorodeoxyglucose F18, Magnetic Resonance Imaging, Pancreas, Positron-Emission Tomography, Tomography, X-Ray Computed

Abstract

Context An intraductal oncocytic papillary neoplasm is a rare pancreatic tumor with the potential of developing invasive carcinoma. Its differentiation from other cystic-like neoplasms of the pancreas, such as intraductal papillary mucinous neoplasms, is a challenge for pancreatic imaging. Case report We present the case of a 76-year-old male with painless jaundice caused by an intraductal oncocytic papillary neoplasm of the pancreas. The imaging findings on computed tomography, magnetic resonance including diffusion-weighted imaging, and 18F-fluorodeoxyglucose positron emission tomography are presented and the radio-pathological correlations are discussed. Conclusion An intraductal oncocytic papillary neoplasm of the pancreas appears as a cystic tumor communicating with the dilated pancreatic duct featuring intraductal tumor nodules. Intraductal oncocytic papillary neoplasms show a high 18F-fluorodeoxyglucose-uptake in positron emission tomography and low diffusion values in diffusion-weighted imaging including apparent diffusion coefficient maps which may be a valuable attribute in distinguishing these rare lesions from intraductal papillary mucinous neoplasms.

Image: Original attenuation-corrected coronal PET image.

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Original attenuation-corrected coronal PET image
Published
2016-07-13
How to Cite
FischerM., DonatiO., HeinrichS., WeberA., HanyT., SoldiniD., AlkadhiH., MarincekB., & ScheffelH. (2016). Intraductal Oncocytic Papillary Neoplasm of the Pancreas: A Radio-Pathological Case Study. JOP. Journal of the Pancreas, 11(1), 49-54. https://doi.org/10.6092/1590-8577/3871
Section
CASE REPORTS