Brunner’s Glands Hyperplasia: Diagnosis with EUS-FNA for Suspected Pancreatic Tumor Involving the Duodenum

  • Monica Arena Gastrointestinal Endoscopy, San Paolo Universitary Hospital. Milan, Italy
  • Stefania Rossi Department of Pathology, San Paolo Universitary Hospital. Milan, Italy
  • Elisabetta Morandi Gastrointestinal Endoscopy, San Paolo Universitary Hospital. Milan, Italy
  • Benedetto Mangiavillano Gastrointestinal Endoscopy, San Paolo Universitary Hospital. Milan, Italy
  • Paolo Franchi Department of Surgery, San Paolo Universitary Hospital. Milan, Italy
Keywords: Brunner Glands, Endosonography, Hyperplasia, Pancreatitis

Abstract

Context Brunner’s gland hyperplasia is a rare, benign, proliferative disorder of the duodenum. Large masses may cause obstructive and compressive symptoms which may depend upon the location of the tumour. Owing to its rarity, these lesions can be mistaken for malignancy on radiological and endoscopic examinations. Symptomatic Brunner’s gland hyperplasia associated with pancreatitis is very rare and the literature is limited to a few case reports endoscopic ultrasound may be useful to obtain a correct diagnosis. Case report We describe an unusual case of diffuse Brunner’s gland hyperplasia of duodenum mimicking a malignancy involving the pancreas, in which EUS-FNA avoided a possible major surgery. Conclusion Brunner’s gland hyperplasia imaging is very similar to malignant pancreatic mass; EUS with FNA is mandatory to reach a correct diagnosis, avoiding surgery.

Image: Endoscopic findings of duodenal sub-stenosis.

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References

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Endoscopic findings of duodenal sub-stenosis
Published
2012-11-10
How to Cite
ArenaM., RossiS., MorandiE., MangiavillanoB., & FranchiP. (2012). Brunner’s Glands Hyperplasia: Diagnosis with EUS-FNA for Suspected Pancreatic Tumor Involving the Duodenum. JOP. Journal of the Pancreas, 13(6), 684-686. https://doi.org/10.6092/1590-8577/970