Rare Solid Tumors of the Pancreas as Differential Diagnosis of Pancreatic Adenocarcinoma

  • Sabine Kersting Department of General and Visceral Surgery, St. Josef-Hospital, Ruhr-University Bochum. Bochum, Germany
  • Monika S Janot Department of General and Visceral Surgery, St. Josef-Hospital, Ruhr-University Bochum. Bochum, Germany
  • Johanna Munding Department of Pathology, Ruhr-University Bochum. Bochum, Germany
  • Dominique Suelberg Department of General and Visceral Surgery, St. Josef-Hospital, Ruhr-University Bochum. Bochum, Germany
  • Andrea Tannapfel Department of Pathology, Ruhr-University Bochum. Bochum, Germany
  • Ansgar M Chromik Department of General and Visceral Surgery, St. Josef-Hospital, Ruhr-University Bochum. Bochum, Germany
  • Waldemar Uhl Department of General and Visceral Surgery, St. Josef-Hospital, Ruhr-University Bochum. Bochum, Germany
  • Uwe Bergmann Department of General and Visceral Surgery, St. Josef-Hospital, Ruhr-University Bochum. Bochum, Germany

Abstract

Context Rare solid tumors of the pancreas can be misinterpreted as primary pancreatic cancer. Objective The aim of this study was to report our experience in the treatment of patients with rare tumor lesions of the pancreas and to discuss clinical and pathological characteristics in the context of the role of surgery. Design Data from patients of our prospective data-base with rare benign and malignant tumors of the pancreas, treated in our division from January 2004 to August 2010, were analyzed retrospectively. Results One-thousand and ninety-eight patients with solid tumors of the pancreas underwent pancreatic surgery. In 19 patients (10 women, 9 men) with a mean age of 57 years (range: 20-74 years) rare pancreatic tumors (metastasis, solid pseudopapillary tumor, teratoma, hemangioma, accessory spleen, lymphoepithelial cyst, hamartoma, sarcoidosis, yolk sac tumor) were the reason for surgical intervention. Conclusion If rare benign and malignant pancreatic tumors, intrapancreatic metastasis, as well as pancreatic malformations or other abnormalities, present themselves as solid masses of the pancreas, they constitute an important differential diagnosis to primary pancreatic neoplasia, e.g. pancreatic ductal adenocarcinoma. Clinical imaging techniques cannot always rule out malignancy, thus operative exploration often remains the treatment of choice to provide the correct diagnosis and initiate adequate surgical therapy.

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Author Biographies

Sabine Kersting, Department of General and Visceral Surgery, St. Josef-Hospital, Ruhr-University Bochum. Bochum, Germany

Department of General Surgery
M.D.

S. Kersting and M. Janot contributed equally.

Monika S Janot, Department of General and Visceral Surgery, St. Josef-Hospital, Ruhr-University Bochum. Bochum, Germany

Department of General Surgery
M.D.

S. Kersting and M. Janot contributed equally.

Johanna Munding, Department of Pathology, Ruhr-University Bochum. Bochum, Germany
Department of Pathology
M.D.
Dominique Suelberg, Department of General and Visceral Surgery, St. Josef-Hospital, Ruhr-University Bochum. Bochum, Germany
Department of General Surgery
M.D.
Andrea Tannapfel, Department of Pathology, Ruhr-University Bochum. Bochum, Germany
Department of Pathology
M.D.
Ansgar M Chromik, Department of General and Visceral Surgery, St. Josef-Hospital, Ruhr-University Bochum. Bochum, Germany
Department of General Surgery
M.D.
Waldemar Uhl, Department of General and Visceral Surgery, St. Josef-Hospital, Ruhr-University Bochum. Bochum, Germany
Department of General Surgery
M.D.

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Intrapancreatic accessory spleen.
Published
2012-05-10
How to Cite
Kersting, S., Janot, M., Munding, J., Suelberg, D., Tannapfel, A., Chromik, A., Uhl, W., & Bergmann, U. (2012). Rare Solid Tumors of the Pancreas as Differential Diagnosis of Pancreatic Adenocarcinoma. JOP. Journal of the Pancreas, 13(3), 268-277. https://doi.org/10.6092/1590-8577/791
Section
ORIGINAL ARTICLES