Heterotopic Pancreas of the Gallbladder Associated with Chronic Cholecystitis and High Levels of Amylasuria

  • Thanasis Klimis Department of Surgery; General Hospital “Polykliniki”; Athens; Greece
  • Nikolaos Roukounakis
  • Ilias Kafetzis
  • Vasileios Mouziouras
  • Ilias Karantonis
  • Nikolaos Andromanakos
Keywords: Choristoma, Gallbladder, Immunohistochemistry, Pancreas

Abstract

Context Heterotopic pancreas of the gallbladder is an extremely rare entity, especially when pancreatic tissue appears histologically with an exclusively exocrine structure. Case report We report the case of a 35-year-old man who presented with symptoms of acalculous gallbladder disease with high levels of amylasuria. Immunohistochemical analysis of the surgical specimen of a cholecystectomy revealed pancreatic tissue at the gallbladder wall. Conclusions Heterotopic pancreatic tissue is a rare pathological finding in the gallbladder. It requires consideration and sensitization in the differential diagnosis of acalculous gallbladder disease, which can explain hyperamylasuria in cases of unknown origin.

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Pancreatic tissue was reactive to alpha-1-chymotrypsin, demonstrating exocrine activity
Published
2011-08-10
How to Cite
KlimisT., RoukounakisN., KafetzisI., MouziourasV., KarantonisI., & AndromanakosN. (2011). Heterotopic Pancreas of the Gallbladder Associated with Chronic Cholecystitis and High Levels of Amylasuria. JOP. Journal of the Pancreas, 12(5), 458-460. https://doi.org/10.6092/1590-8577/450