Diffuse Pancreatic Lesion Mimicking Autoimmune Pancreatitis in an HIV-Infected Patient: Successful Treatment by Antiretroviral Therapy

  • Gil Leurquin-Sterk Erasme Hospital; 808 route de Lennik; 1070 Brussels; Belgium
  • Kinda Schepers
  • Myriam Delhaye
  • Serge Goldman
  • Laurine Verset
  • Celso Matos
Keywords: Acquired Immunodeficiency Syndrome, Inflammation, Magnetic Resonance Imaging, Pancreatitis, Positron-Emission Tomography

Abstract

Context Pancreatitis is a common complication of acquired immunodeficiency syndrome. The most common causes of acute pancreatitis in an HIV population are medication and opportunistic infections. Case report We report the case of a young, untreated, HIV-infected female who presented with acute pancreatitis of unknown origin. Unique to this case are the autoimmune pancreatitis-like features on imaging studies associated with renal mass-like lesions and lymph node involvement as well as the favorable outcome using highly active antiretroviral therapy alone. Conclusion In HIV-infected patients, acute pancreatitis may present on imaging studies as autoimmune pancreatitis. In patients with uncontrolled HIV infection and imaging studies suggestive of autoimmune pancreatitis, direct HIV-related inflammation should be considered after exclusion of all other causes of pancreatitis.

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Fusion of axial MRI T2-weighted spin-echo and diffusion-weighted image showing complete resolution of the pancreatic lesions and dramatic regression of the right kidney lesion
Published
2011-09-14
How to Cite
Leurquin-SterkG., SchepersK., DelhayeM., GoldmanS., VersetL., & MatosC. (2011). Diffuse Pancreatic Lesion Mimicking Autoimmune Pancreatitis in an HIV-Infected Patient: Successful Treatment by Antiretroviral Therapy. JOP. Journal of the Pancreas, 12(5), 477-481. https://doi.org/10.6092/1590-8577/457