New Therapeutic Strategies in the Second Line Setting of Advanced or Metastatic Pancreatic Adenocarcinoma

  • Vasilis Stefanos Ramfidis University of Pittsburgh Cancer Institute. Pittsburgh, PA, USA.
  • Kostas N Syrigos Oncology Unit, Third Department of Medicine, University of Athens, Sotiria General Hospital. Athens, Greece.
  • Muhammad Wasif Saif Department of Medicine and Cancer Center, Tufts Medical Center. Boston, MA, USA
Keywords: Antineoplastic Agents, Drug Therapy, Pancreatic Neoplasms

Abstract

Pancreatic cancer is a lethal disease and its prognosis remains dismal. The modest results of existing available treatments in the second line setting reveal the need of new therapeutic strategies. In this year’s American Society of Clinical Oncology (ASCO) Annual Meeting two remarkable trials and one retrospective analysis were presented regarding this vulnerable group of patients. According to the published results, docetaxel plus oxaliplatin (Abstract #4034), selumetinib plus erlotinib (Abstract #4014) and nab-paclitaxel (Abstract #e15057) have shown promising efficacy and manageable toxicity that should be elucidated and confirmed by new prospective, large, randomized trials.

Image: Therapeutic strategies in second line setting of advanced or metastatic pancreatic adenocarcinoma.

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References

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Therapeutic strategies in second line setting of advanced or metastatic pancreatic adenocarcinoma
Published
2013-07-10
How to Cite
Ramfidis, V., Syrigos, K., & Saif, M. (2013). New Therapeutic Strategies in the Second Line Setting of Advanced or Metastatic Pancreatic Adenocarcinoma. JOP. Journal of the Pancreas, 14(4), 344-346. https://doi.org/10.6092/1590-8577/1650
Section
Highlights from the “2013 ASCO Annual Meeting”. Chicago, IL, USA. May 31 - June 4, 2013

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