Tumor Markers in Pancreatic Cancer: 2013

  • Urvi Ajay Shah Tufts Medical Center. Boston, MA, USA
  • Muhammad Wasif Saif Tufts Medical Center. Boston, MA, USA
Keywords: CA-19-9 Antigen, Pancreatic Neoplasms, Prognosis

Abstract

Amongst the tumor markers for pancreatic cancer CA 19-9 is being used most widely and newer clinically useful applications of this tumor marker are being researched. We will discuss four abstracts presented at the American Society of Clinical Oncology (ASCO) Annual Meeting which contribute to expanding the application of CA 19-9 measurement (Abstracts #4042, #4058, #e15082, #e15146).

Image: Sequence of therapeutic interventions and subsequent mean CA19-9 measurements.

 

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Author Biographies

Urvi Ajay Shah, Tufts Medical Center. Boston, MA, USA
Internal Medicine Resident, Department of Internal Medicine, Tufts Medical Center, 800 Washington Street, Boston, MA 02111, USA
Muhammad Wasif Saif, Tufts Medical Center. Boston, MA, USA

Director, Section of GI Cancers and Experimental Therapeutics, Tufts University School of Medicine and

Tufts Cancer Center

800 Washington Street, Boston, MA 02111, USA

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Nakai, Y., et al., A retrospective analysis of early CA 19-9 progression in salvage chemotherapy for refractory pancreatic cancer. Journal of Clinical Oncology 31, 2013 (suppl; abstr e15146)

Chiorean, E. G., et al., CA 19-9 decrease at 8 weeks as a predictor of overall survival (OS) in a randomized phase III trial (MPACT) of weekly nab-paclitaxel (nab-P) plus gemcitabine (G) versus G alone in patients with metastatic pancreatic cancer (MPC.) Journal of Clinical Oncology 31, 2013 (suppl; abstr 4058)

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Heymach J., et al, Circulating cytokines and angiogenic factors (CAF) as markers of clinical response in the study of trametinib (T) plus gemcitabine (G) versus placebo (P) plus gemcitabine for patients (pts) with untreated metastatic adenocarcinoma of the pancreas (MEK113487). Journal of Clinical Oncology 31, 2013 (suppl; abstr 4042)

Sequence of therapeutic interventions and subsequent mean CA19-9 measurements
Published
2013-07-10
How to Cite
ShahU., & SaifM. (2013). Tumor Markers in Pancreatic Cancer: 2013. JOP. Journal of the Pancreas, 14(4), 318-321. https://doi.org/10.6092/1590-8577/1653
Section
Highlights from the “2013 ASCO Annual Meeting”. Chicago, IL, USA. May 31 - June 4, 2013

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