U.S. Food and Drug Administration Approves Paclitaxel Protein-Bound Particles (Abraxane®) in Combination with Gemcitabine as First-Line Treatment of Patients with Metastatic Pancreatic Cancer

  • Muhammad Wasif Saif Tufts University School of Medicine. Boston, MA, USA
Keywords: Carcinoma, Drug Therapy, gemcitabine, Neoplasm Metastasis, Pancreas, Pancreatic Neoplasms, Therapeutics

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References

Von Hoff DD, Ramanathan RK, Borad MJ, Laheru DA, Smith LS, Wood TE, et al. Gemcitabine plus nab-paclitaxel is an active regimen in patients with advanced pancreatic cancer: a phase I/II trial. J Clin Oncol 2011; 29:4548-54. [PMID 21969517]

Von Hoff DD, Ervin T, Arena FP, Chiorean EG, Infante J, Moore M, et al. Increased survival in pancreatic cancer with nab-paclitaxel plus gemcitabine. N Engl J Med 2013; Oct 16. [PMID 24131140]

Therasse P, Arbuck SG, Eisenhauer EA, Wanders J, Kaplan RS, Rubinstein L, et al. New guidelines to evaluate the response to treatment in solid tumors. European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada. J Natl Cancer Inst 2000; 92:205-16. [PMID 10655437]

U.S. Food and Drug Administration. FDA approved drug products: Abraxane. Label Information. September 6th, 2013.

Conroy T, Desseigne F, Ychou M, Bouché O, Guimbaud R, Bécouarn Y, et al. FOLFIRINOX versus gemcitabine for metastatic pancreatic cancer. N Engl J Med 2011; 364:1817-25. [PMID 21561347]

Pollack A. Drug is shown to help pancreatic cancer cases. The New York Time 2013; January 22. (Last accessed on October 26, 2013)

Pancreas news
Published
2013-11-10
How to Cite
SaifM. (2013). U.S. Food and Drug Administration Approves Paclitaxel Protein-Bound Particles (Abraxane®) in Combination with Gemcitabine as First-Line Treatment of Patients with Metastatic Pancreatic Cancer. JOP. Journal of the Pancreas, 14(6), 686-688. https://doi.org/10.6092/1590-8577/2028

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