Endoluminal Ultrasound of Neoduodenum Following Pancreas-Preserving Total Duodenectomy for Familial Adenomatous Polyposis

  • Andrew J Beamish Department of General Surgery, Morriston Hospital, ABM University Health Board, Swansea. UK.
  • S Ashley Roberts
  • James Ansell
  • Bilal Al-Sarireh Department of General Surgery, Morriston Hospital, ABM University Health Board, Swansea. UK
Keywords: Adenomatous Polyposis Coli, Biopsy, Fine-Needle, Duodenal Neoplasms, Endoscopy, Endosonography, Pancreaticoduodenectomy


Context Familial adenomatous polyposis affects around 2-10 per 100,000 population. Untreated, it inevitably leads to colon cancer. Prophylactic panproctocolectomy has led to improved survival. The resulting extension to follow-up has revealed that 70-100% of patients with familial adenomatous polyposis go on to develop duodenal polyposis and the lifetime risk of duodenal carcinoma in this group is up to 10%. Treatment for those not locally resectable requires pancreaticoduodenectomy. In recent years, pancreas-preserving total duodenectomy has emerged as a safe alternative to pancreaticoduodenectomy. Endoscopy has previously been safely performed in patients following pancreas-preserving total duodenectomy. Case report We report successful endoscopic ultrasound (EUS) assessment and trans-neoduodenal EUS-guided fine needle aspiration biopsy (EUS-FNA) of the pancreas and adjacent tissue in a 45-year-old man with familial adenomatous polyposis who has previously undergone pancreas-preserving total duodenectomy. EUS confirmed the mass was most likely to represent a metastasis in a local lymph node. EUS-FNA confirmed invasive malignancy. A Kausch-Whipple pancreaticoduodenectomy was performed successfully and post-operative recovery has been excellent. Conclusion The authors consider this to be the first report of successful EUS and EUS-FNA performed through the neoduodenum fashioned during pancreas-preserving total duodenectomy.


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European Medicines Agency. Document Reference: EMEA/COMP/264/04draft (online 2009). http://www.emea.europa.eu

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Hypoechoic mass with a 22-gauge needle clearly seen within the lesion
How to Cite
BeamishA., RobertsS., AnsellJ., & Al-SarirehB. (2012). Endoluminal Ultrasound of Neoduodenum Following Pancreas-Preserving Total Duodenectomy for Familial Adenomatous Polyposis. JOP. Journal of the Pancreas, 13(1), 98-100. https://doi.org/10.6092/1590-8577/471