In these last ten years, TeMA Journal has published several international studies and researches supporting the scientific debate on the urban complexity and the future challenges of urban areas. Thus, the three issues of the 12th volume will think again about the debate on the definition and implementation of methods, tools and best practices connected to the evolution of the main scientific topics examined in depth in previous TeMA Journal volumes. In detail, the Journal welcomes papers on topics about the interdisciplinary interaction among Land Use, Mobility and Environment, and also urban studies from the domains of engineering, planning, modelling, behaviour, regional economics, geography, regional science, architecture and design, network science, complex systems, energy efficiency, urban accessibility, resilience and adaptation.